(αS)​-α-​Methoxy-​N-​(tetrahydro2-​oxo-​3-​thienyl)​benzeneacetamide

Ref. TR-M124275

Produktinformation

• Name: (αS)​-α-​Methoxy-​N-​(tetrahydro2-​oxo-​3-​thienyl)​benzeneacetamide
• Synonyme: (2S)-2-methoxy-N-(2-oxothiolan-3-yl)-2-phenylacetamide

Beschreibung

Applications (αS)​-α-​Methoxy-​N-​(tetrahydro2-​oxo-​3-​thienyl)​benzeneacetamide is an intermediate in the synthesis of D-Homocysteine Thiolactone Hydrochloride (H591320), which is a moderate mGlu receptor agonist and thus suggests that moderate hyperhomocysteinemia may be associated with several diseases including coronoary artery, Alzheimer’s disease and schizophrenia.
References Shi, Q. et al.: J. Pharmacol. Exp. Thera., 305, 131 (2003);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 265.328
• Formel: C₁₃H₁₅NO₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C13H15NO3S/c1-17-11(9-5-3-2-4-6-9)12(15)14-10-7-8-18-13(10)16/h2-6,10-11H,7-8H2,1H3,(H,14,15)/t10?,11-/m0/s1
• InChI Key: InChIKey=ZRHOJYWAJZLYKG-DTIOYNMSSA-N
• SMILES: CO[C@H](C(=O)NC1CCSC1=O)c1ccccc1