1-​Methyl-​5-​(4-​morpholinyl)​-1H-​benzimidazole-​2-​butanoic Acid Ethyl Ester

CAS: 1366085-75-7

Ref. TR-M136605

Produktinformation

• Name: 1-​Methyl-​5-​(4-​morpholinyl)​-1H-​benzimidazole-​2-​butanoic Acid Ethyl Ester
• Synonyme: Bendamustine Impurity 27 Ethyl Ester

Beschreibung

Applications 1-​Methyl-​5-​(4-​morpholinyl)​-1H-​benzimidazole-​2-​butanoic Acid Ethyl Ester is an intermediate in the synthesis of 4-(1-Methyl-5-morpholino-1H-benzo[d]imidazol-2-yl)butanoic Acid (Bendamustine Impurity 27) (M234490), which is an impurity of Bendamustine (B132500), which is used as an anticancer drug.
References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 331.41
• Formel: C₁₈H₂₅N₃O₃
• Farbe/Form: Off White Solid
• InChl: InChI=1S/C18H25N3O3/c1-3-24-18(22)6-4-5-17-19-15-13-14(7-8-16(15)20(17)2)21-9-11-23-12-10-21/h7-8,13H,3-6,9-12H2,1-2H3
• InChI Key: InChIKey=WCCZECQJGWCKDG-UHFFFAOYSA-N
• SMILES: CCOC(=O)CCCc1nc2cc(N3CCOCC3)ccc2n1C