Mangafodipir Trisodium

CAS: 140678-14-4

Ref. TR-M163700

Produktinformation

• Name: Mangafodipir Trisodium
• Synonyme: Manganate(6-), [[rel-[N(R),N'(R)]-N,N'-1,2-ethanediylbis[N-[[3-(hydroxy-?O)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-?N,?O]](8-)]-, sodium hydrogen (1:3:3), (OC-6-13)-, Manganate(6-), [[N,N'-1,2-ethanediylbis[N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato]](8-)]-, trisodium trihydrogen, (OC-6-13)-, Manganate(6-), [[rel-[N(R),N'(R)]-N,N'-1,2-ethanediylbis[N-[[3-(hydroxy-?O)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-?N,?O]](8-)]-, trisodium trihydrogen, (OC-6-13)- (9CI), MnDPDP, S 095, Teslascan, Win 59010, Mangafodipir Trisodium [USAN], Manganate(6-), ((N,N'-1,2-ethanediylbis(N-((3-hydroxy-2-methyl-5-((phosphonooxy)-methyl)-4-pyridinyl)methyl)glycinato)) (8-))-, trisodium trihydrogen, (OC-6-13)-, Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, sodium hydrogen (1:3:3), (OC-6-13)-, Manganate(6-), [[rel-[N(R),N′(R)]-N,N′-1,2-ethanediylbis[N-[[3-(hydroxy-κO)-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methyl]glycinato-κN,κO]](8-)]-, trisodium trihydrogen, (OC-6-13)-, Manganese(2+) Sodium Hydrogen 2,2'-{Ethane-1,2-Diylbis[({2-Methyl-3-Oxido-5-[(Phosphonatooxy)Methyl]Pyridin-4-Yl}Methyl)Imino]}Diacetate (1:3:3:1), Trisodium trihydrogen (OC-6-13)-((N,N'-1,2-ethanediylbis(N-((3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methyl)glycinato))(8-)manganate(6-), Trisodium trihydrogen (OC-6-13)-((N,N'-ethylenebis(N-((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridyl)methyl)glycine) 5,5'-bis(phosphato))(8-))manganate(6-), Unii-129Fw80Tg4

Beschreibung

Applications Mangafodipir Trisodium is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. It protects against hepatic ischemia-reperfusion injury in mice and decreases hematotoxicity and enhanced cytotoxicity of anticancer agents.
References Ben Mosbah, I., et al.: PLoS One, 7, e50235 (2012); Coriat, R., et al.: PLoS One, 6, e27005 (2011); Alexandre, J., et al.: J. Natl. Cancer I., 98, 236 (2006); Traore, A.S., et al.: Magn. Reson. Imaging, 21, 609 (2003)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 757.32
• Formel: C₂₂H₂₇MnN₄O₁₄P₂Na
• Farbe/Form: Light Yellow To Yellow
• InChl: , , , , InChI=1S/C22H32N4O14P2.Mn.3Na/c1-13-21(31)17(15(5-23-13)11-39-41(33,34)35)7-25(9-19(27)28)3-4-26(10-20(29)30)8-18-16(12-40-42(36,37)38)6-24-14(2)22(18)32, /h5-6,31-32H,3-4,7-12H2,1-2H3,(H,27,28)(H,29,30)(H2,33,34,35)(H2,36,37,38), +2, /q, , , 3*+1/p-5
• SMILES: Cc1ncc(COP(=O)([O-])O)c(CN(CCN(CC(=O)[O-])Cc2c(COP(=O)(O)O)cnc(C)c2[O-])CC(=O)[O-])c1[O-].[Mn+2].[Na+].[Na+].[Na+]