3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone-D6

CAS: 10320-49-7

Ref. TR-M205301

Produktinformation

• Name: 3-(Dimethylamino)-1-(1-naphthalenyl)-1-propanone-D6
• Synonyme: 3-[bis(trideuteriomethyl)amino]-1-naphthalen-1-ylpropan-1-one, 1-Propanone, 3-(Dimethylamino)-1-(1-Naphthalenyl)-, 3-(Dimethylamino)-1-(1-naphthyl)propan-1-on, 3-(Dimethylamino)-1-(1-naphthyl)propan-1-one, 3-(Dimethylamino)-1-(Naphthalen-1-Yl)Propan-1-One

Beschreibung

Applications 3-(Dimethylamino)-1-(1-Naphthalenyl)-1-Propanone-D6 is a reagent in the synthesis of Bedaquiline-d6 (Mixture of Diastereomers) (B119552) which is the labelled analog of Bedaquiline, a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 233.339
• Formel: C₁₅D₆H₁₁NO
• Farbe/Form: Neat
• InChl: InChI=1S/C15H17NO/c1-16(2)11-10-15(17)14-9-5-7-12-6-3-4-8-13(12)14/h3-9H,10-11H2,1-2H3/i1D3,2D3
• InChI Key: InChIKey=CXDXSNWZXJVDMC-WFGJKAKNSA-N
• SMILES: [2H]C([2H])([2H])N(CCC(=O)c1cccc2ccccc12)C([2H])([2H])[2H]