Mergetpa

CAS: 77102-28-4

Ref. TR-M225170

Produktinformation

• Name: Mergetpa
• Synonyme: 3-[[2-[(Aminoiminomethyl)amino]ethyl]thio]-2-(mercaptomethyl)propanoic Acid, (±)-2-(Mercaptomethyl)-3-(guanidinoethylthio)propionic Acid, DL-2-(Mercaptomethyl)-3-(guanidinoethyl)thiopropanoic Acid, Plummer's Carboxypeptidase Inhibitor

Beschreibung

Stability Air Sensitive, Hygroscopic
Applications Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.
References Barenholz, Y., et al.: Biochemistry, 16, 2806 (1977), Eaton, D., et al.: J. Biol. Chem., 266, 21833 (1991), Tan, A., et al.: Biochemistry, 34, 5811 (1995),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 237.34
• Formel: C₇H₁₅N₃O₂S₂
• Farbe/Form: Neat
• InChl: InChI=1S/C7H15N3O2S2/c8-7(9)10-1-2-14-4-5(3-13)6(11)12/h5,13H,1-4H2,(H,11,12)(H4,8,9,10)
• InChI Key: InChIKey=AKPKWZRKZOAAAZ-UHFFFAOYSA-N
• SMILES: NC(N)=NCCSCC(CS)C(=O)O