D-Methionine-d4

CAS: 348-67-4

Ref. TR-M260552

Produktinformation

• Name: D-Methionine-d4
• Synonyme: S-Methyl-D-homocysteine-d4,D-Methionine-3,3,4,4-d4, D-Methionine-3,3,4,4-D4, (2R)-2-Amino-4-methylsulfanylbutanoic-3,3,4,4-d4 acid, (R)-2-Amino-4-(methylthio)butanoic-3,3,4,4-d4 acid, (2R)-2-Amino-4-methylsulfanylbutanoic acid, (R)-2-Amino-4-(Methylmercapto)Butyric Acid, (R)-2-Amino-4-(methylthio)butanoic acid, (R)-Methionine, <span class="text-smallcaps">D</span>-Methionine, D-2-Amino-4-(Methylthio)Butyric Acid, D-Methionin, D-metionina, H-D-Met-OH, Methionine, <span class="text-smallcaps">D</span>-, Methionine, D-, Mrx 1024, Nsc 45689, S-Methyl-<span class="text-smallcaps">D</span>-homocysteine, S-Methyl-D-homocysteine, D-Methionine

Beschreibung

Applications D-Methionine-d4 is labelled D-Methionine (M260550), an isomer of L-Methionine (M260440) which is a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
References Campbell, K., et al.: Hear. Res., 92, 103 (2007); Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 153.24
• Formel: C₅D₄H₇NO₂S
• Farbe/Form: Neat
• InChl: InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1/i2D2,3D2
• InChI Key: InChIKey=SIAVJTYUIMDRNA-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)CCN1Cc3c(ccc(OC)c3OS(=O)(=O)c3cccc(F)c3)CC21