Methotrexate γ-Methyl Ester

CAS: 67022-39-3

Ref. TR-M260705

Produktinformation

• Name: Methotrexate γ-Methyl Ester
• Synonyme: L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 5-methyl ester, Methotrexate 5-Methyl Ester, Methotrexate Imp. H (EP), (2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic Acid
• Marke: TRC
• Beschreibung: Impurity Methotrexate EP Impurity HApplications Methotrexate γ-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),

Chemische Eigenschaften

• Molekulargewicht: 468.47
• Formel: C₂₁H₂₄N₈O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C21H24N8O5/c1-29(10-12-9-24-18-16(25-12)17(22)27-21(23)28-18)13-5-3-11(4-6-13)19(31)26-14(20(32)33)7-8-15(30)34-2/h3-6,9,14H,7-8,10H2,1-2H3,(H,26,31)(H,32,33)(H4,22,23,24,27,28)/t14-/m0/s1
• InChI Key: InChIKey=RYGFOBBTCUXHBB-AWEZNQCLSA-N
• SMILES: COC(=O)CC[C@H](NC(=O)c1ccc(N(C)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)O