Methotrexate Hexaglutamate Trifluoroacetate

CAS: 80801-53-2

Ref. TR-M260745

Produktinformation

• Name: Methotrexate Hexaglutamate Trifluoroacetate
• Synonyme: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-?-glutamyl-L-?-glutamyl-L-?-glutamyl-L-?-glutamyl-L-?-glutamyl-L-glutamic Acid Trifluoroacetate, N-[N-[N-[N-[N-[N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-?-glutamyl]-L-?-glutamyl]-L-?-glutamyl]-L-?-glutamyl]-L-?-glutamyl]-L-glutamic Acid Trifluoroacetate

Beschreibung

Stability Hygroscopic
Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 1214.03
• Formel: C₄₅H₅₇N₁₃O₂₀·x(C₂HF₃O₂)
• Farbe/Form: Yellow Solid
• InChl: InChI=1S/C45H57N13O20.C2HF3O2/c1-58(19-21-18-48-37-35(49-21)36(46)56-45(47)57-37)22-4-2-20(3-5-22)38(66)55-28(44(77)78)10-16-33(63)53-26(42(73)74)8-14-31(61)51-24(40(69)70)6-12-29(59)50-23(39(67)68)7-13-30(60)52-25(41(71)72)9-15-32(62)54-27(43(75)76)11-17-34(64)65;3-2(4,5)1(6)7/h2-5,18,23-28H,6-17,19H2,1H3,(H,50,59)(H,51,61)(H,52,60)(H,53,63)(H,54,62)(H,55,66)(H,64,65)(H,67,68)(H,69,70)(H,71,72)(H,73,74)(H,75,76)(H,77,78)(H4,46,47,48,56,57);(H,6,7)/t23-,24-,25-,26-,27-,28-;/m0./s1
• SMILES: NNC(=O)C[n+]1ccccc1.[Cl-]