1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester

CAS: 916332-38-2

Ref. TR-M261315

Produktinformation

• Name: 1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester
• Synonyme: methyl 3-[[4-(2-methoxycarbonylphenyl)phenyl]methyl]-7-methyl-2-propylbenzimidazole-5-carboxylate
• Marke: TRC
• Beschreibung: Applications 1-[[2'-(Methoxycarbonyl)[1,1'-biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester is an intermediate in the synthesis of Telmisartan (T017000), an angiotensin II receptor antagonist.References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)

Chemische Eigenschaften

• Molekulargewicht: 456.53
• Formel: C₂₈H₂₈N₂O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C28H28N2O4/c1-5-8-25-29-26-18(2)15-21(27(31)33-3)16-24(26)30(25)17-19-11-13-20(14-12-19)22-9-6-7-10-23(22)28(32)34-4/h6-7,9-16H,5,8,17H2,1-4H3
• InChI Key: InChIKey=UZTLLOMIRYFGLV-UHFFFAOYSA-N
• SMILES: CCCc1nc2c(C)cc(C(=O)OC)cc2n1Cc1ccc(-c2ccccc2C(=O)OC)cc1