3-Methyl Adenine-d3

CAS: 110953-39-4

Ref. TR-M275905

Produktinformation

• Name: 3-Methyl Adenine-d3
• Synonyme: 3-(trideuteriomethyl)purin-6-amine

Beschreibung

Applications 3-Methyl Adenine-d3 is labelled 3-Methyl Adenine (M275904). 3-Methyl Adenine is a selective autophagy and phosphoinositide 3-kinase (PI3K) inhibitor (1,2,3). 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K).
References (1) Munafo, D., et al.: J. Cell Sci., 114, 3619 (2001) (2) Aggarwal, B., et al.: Biochem. Pharmacol., 71, 1397 (2006) (3) Hayat, M., et al.: Oncologist, 12, 20 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 152.17
• Formel: C₆H₃H₄N₅
• Farbe/Form: Neat
• InChl: InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3/i1D3
• InChI Key: InChIKey=FSASIHFSFGAIJM-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])n1cnc(N)c2ncnc1-2