1-Methyl Adenosine-d3

CAS: 15763-06-1

Ref. TR-M285067

Produktinformation

• Name: 1-Methyl Adenosine-d3
• Synonyme: (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol-d3, (6Z)-1-methyl-9-pentofuranosyl-1,9-dihydro-6H-purin-6-imine, 1-Methyladenosine, 9H-Purine, 1,6-dihydro-6-imino-1-methyl-9-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Adenosine, 1-methyl-, Adenosine, 1-methyl- (VAN) (8CI), Adenosine, N,6-didehydro-1,6-dihydro-1-methyl- (9CI), N1-Methyladenosine, N¹-Methyladenosine, Nsc 92165, 9H-Purine, 1,6-dihydro-6-imino-1-methyl-9-β-D-ribofuranosyl-

Beschreibung

Applications 1-Methyl Adenosine-d3 is the isotope labelled analog of 1-Methyl Adenosine (M285065); a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.
References Wu, Q. et al.: Anal. Chem., 86, 10122 (2014); Puri, P. et al.: Mol. Microbiol., 93, 944 (2014)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 284.29
• Formel: C₁₁H₁₂D₃N₅O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1/i1D3
• InChI Key: InChIKey=GFYLSDSUCHVORB-YZLHILBGSA-N
• SMILES: [2H]C([2H])([2H])n1cnc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1=N