6,​6'-​Methylenebis[5,​6,​7,​8-​tetrahydro-1,​3-​dioxolo[4,​5-​g]​isoquinoline

CAS: 1005328-62-0

Ref. TR-M288963

Produktinformation

• Name: 6,​6'-​Methylenebis[5,​6,​7,​8-​tetrahydro-1,​3-​dioxolo[4,​5-​g]​isoquinoline
• Synonyme: bis(7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6(5H)-yl)methane
• Marke: TRC

Beschreibung

Applications 6,​6'-​Methylenebis[5,​6,​7,​8-​tetrahydro-1,​3-​dioxolo[4,​5-​g]​isoquinoline is an intermediate in synthesizing (+/-)-β-Hydrastine (H675690), an inhibitor of Dopamine biosynthesis.
References Jones, D., et al.: Drug Metab. Disposition, 35, 1466 (2007); Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010)

Chemische Eigenschaften

• Molekulargewicht: 366.41
• Formel: C₂₁H₂₂N₂O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C21H22N2O4/c1-3-22(9-16-7-20-18(5-14(1)16)24-12-26-20)11-23-4-2-15-6-19-21(27-13-25-19)8-17(15)10-23/h5-8H,1-4,9-13H2
• SMILES: CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(C(=O)Nc3ccccn3)cc2)c2c(N)nccn12