4'-Methylbiphenyl-2-carbonitrile

CAS: 114772-53-1

Ref. TR-M294115

Produktinformation

• Name: 4'-Methylbiphenyl-2-carbonitrile
• Synonyme: [1,1'-Biphenyl]-2-carbonitrile, 4'-methyl-, 4'-Methyl[1,1'-biphenyl]-2-carbonitrile, 2-(4-Methylphenyl)benzonitrile, 2-(p-Tolyl)benzonitrile, 2-Cyano-4'-methyl-1,1'-biphenyl, 2-Cyano-4'-methylbiphenyl, 2'-Cyano-4-methylbiphenyl, 4-Methyl-2'-cyanobiphenyl, 4'-Methyl-1,1'-biphenyl-2-ylcarbonitrile, 4'-Methyl-2-cyanobiphenyl, 2-(4-Methylphenyl)Benzonitrile, 2-(4-Tolyl)-Benzonitrile, 2-Cyamo-4'-methylbiphenyl, 2-Cyano-4'-Methyl Biphenyl, 2-Cyano-4′-methyl-1,1′-biphenyl, 2-Ethynyl-4'-Methylbiphenyl, 4'-Methyl-2-Biphenylcarbonitrile, 4'-Methyl-2-Cyano-Biphenyl (For Losartan), 4'-Methyl-2-Cyanobiphenyl, 4'-Methyl[1,1'-Biphenyl]-2-Carbonitrile, 4'-Methylbiphenyl-2-Carbonitrile, 4′-Methyl-1,1′-biphenyl-2-ylcarbonitrile, Akos Bar-1203, Otbn, Sartanbiphenyl, [1,1′-Biphenyl]-2-carbonitrile, 4′-methyl-, [2-(P-Tolyl)Benzonitrile]

Beschreibung

Applications 4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.
References Lo Monte, F., et al.: J. Med. Chem., 55, 4407 (2012); Schaarschmidt, D., et al.: ACS. Catalysis., 1, 411 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 193.24
• Formel: C₁₄H₁₁N
• Farbe/Form: Neat
• InChl: InChI=1S/C14H11N/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-9H,1H3
• SMILES: Cc1ccc(-c2ccccc2C#N)cc1