3-O-Methyl-L-DOPA Monohydrate

CAS: 200630-46-2

Ref. TR-M303815

Produktinformation

• Name: 3-O-Methyl-L-DOPA Monohydrate
• Synonyme: L-Tyrosine, 3-methoxy-, monohydrate (9CI), 3-Methoxy-L-tyrosine monohydrate, 3-Methoxy-4-hydroxy-L-phenylalanine monohydrate, L-4-Hydroxy-3-methoxyphenylalanine monohydrate, (2S)-2-Amino-3-(4-hydroxy-3-methoxy-phenyl)propanoic acid hydrate (1:1)
• Marke: TRC
• Beschreibung: Applications 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.References Soares-da Silva, P., et al.: Brain Res., 863, 293 (2000), Deleu, D., et al.: Clin. Pharmacokinet., 41, 261 (2002),

Chemische Eigenschaften

• Molekulargewicht: 229.23
• Formel: C₁₀H₁₃NO₄·H₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C10H13NO4.H2O/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14;/h2-3,5,7,12H,4,11H2,1H3,(H,13,14);1H2/t7-;/m0./s1
• InChI Key: InChIKey=IDRRCKUGGXLORG-FJXQXJEOSA-N
• SMILES: COc1cc(C[C@H](N)C(=O)O)ccc1O.O