1-Methyl-L-histidine

CAS: 332-80-9

Ref. TR-M312050

Produktinformation

• Name: 1-Methyl-L-histidine
• Synonyme: Histidine, 1-methyl-, L- (8CI), (S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid, 1-Methylhistidine, 1-N-Methyl-L-histidine, N1-Methyl-L-histidine, NSC 524367, t-Methylhistidine, (2S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid, 1-Methyl-<span class="text-smallcaps">L</span>-histidine, 1-N-Methyl-<span class="text-smallcaps">L</span>-histidine, 1-methyl-L-histidine, <span class="text-smallcaps">L</span>-Histidine, 1-methyl-, Histidine, 1-methyl-, <span class="text-smallcaps">L</span>-, N₁-Methyl-<span class="text-smallcaps">L</span>-histidine, π-N-Methyl-<span class="text-smallcaps">L</span>-histidine, τ-Methylhistidine, L-Histidine, 1-methyl-, Histidine, 1-methyl-, L-

Beschreibung

Applications The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
References Berna, M., et al.: Anal. Chem., 79, 4199 (2007), Pritt, M., et al.: Toxicol. Sci., 103, 382 (2008), Tonomura, Y., et al.: Toxicology, 266, 48 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 169.18
• Formel: C₇H₁₁N₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C7H11N3O2/c1-10-3-5(9-4-10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1
• InChI Key: InChIKey=BRMWTNUJHUMWMS-UHFFFAOYSA-N
• SMILES: Cn1cnc(CC(N)C(=O)O)c1