2-Methyllamotrigine Methanesulfonate

CAS: 1152091-69-4

Ref. TR-M315350

Produktinformation

• Name: 2-Methyllamotrigine Methanesulfonate
• Synonyme: 3,5-Diamino-6-(2,3-dichlorophenyl)-2-methyl-1,2,4-triazinium Methane Sulfonate
• Marke: TRC

Beschreibung

Applications 2-Methyl-Lamotrigine is an impurity of Lamotrigine (L173250), an anticonvulsant which inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Used in treatment of bipolar depression.
References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),

Chemische Eigenschaften

• Molekulargewicht: 366.22
• Formel: C₁₀H₉Cl₂N₅·CH₄O₃S
• Farbe/Form: Mixture
• InChl: InChI=1S/C10H9Cl2N5.CH4O3S/c1-17-10(14)15-9(13)8(16-17)5-3-2-4-6(11)7(5)12;1-5(2,3)4/h2-4H,1H3,(H3,13,14,15);1H3,(H,2,3,4)
• InChI Key: InChIKey=FFIREEFHIDPSTQ-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)O.Cn1nc(-c2cccc(Cl)c2Cl)c(N)nc1=N