Metanicotine

CAS: 15585-43-0

Ref. TR-M321250

Produktinformation

• Name: Metanicotine
• Synonyme: (E)-N-[Methyl]-4-(3-pyridinyl)-3-buten-1-amine, RJR 2403, Rivanicline, (E)-Metanicotine, (3E)-N-Methyl-4-(3-pyridinyl)-3-buten-1-amine, (3E)-N-Methyl-4-(pyridin-3-yl)but-3-en-1-amine, 3-Buten-1-amine, N-methyl-4-(3-pyridinyl)-, (3E)-, 3-Buten-1-amine, N-methyl-4-(3-pyridinyl)-, (E)-, But-3-en-1-amine, N-methyl-4-(pyridin-3-yl)-, (E)-, Pyridine, 3-[4-(methylamino)-1-butenyl]-, (E)-, Rivanicline [INN], Rjr 2403, Unii-6H35Lf645A, trans-Metanicotine
• CAS: 15585-43-0

Beschreibung

Applications An alkaloid found in the leaves of Duboisia Hopwoodii, and a constitutent of tobacco smoke. Also used a potential drug for the treatment of senile dementia of the Alzheimer’s type and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964), Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982), Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993), Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 162.23
• Formel: C₁₀H₁₄N₂
• Farbe/Form: Colourless to Yellow Oil
• InChl: InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3/b5-2+
• InChI Key: InChIKey=JUOSGGQXEBBCJB-GORDUTHDSA-N
• SMILES: CNCC/C=C/c1cccnc1