Metanicotine-d3

CAS: 220088-40-4

Ref. TR-M321252

Produktinformation

• Name: Metanicotine-d3
• Synonyme: (E)-N-[Methyl]-4-(3-pyridinyl)-3-buten-1-amine-d, , RJR 2403-d3, Rivanicline-d3, (E)-Metanicotine-d3
• CAS: 220088-40-4

Beschreibung

Applications Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250); an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer’s type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964); Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982); Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993); Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 165.25
• Formel: C₁₀H₁₁D₃N₂
• Farbe/Form: Colourless Oil
• InChl: InChI=1S/C10H14N2/c1-11-7-3-2-5-10-6-4-8-12-9-10/h2,4-6,8-9,11H,3,7H2,1H3/b5-2+/i1D3
• InChI Key: InChIKey=JUOSGGQXEBBCJB-PAMUQJMYSA-N
• SMILES: [2H]C([2H])([2H])NCC/C=C/c1cccnc1