2-[Methyl(phenylmethyl)amino]ethyl 3-Oxo-butanoic Acid

CAS: 54527-65-0

Ref. TR-M322565

Produktinformation

• Name: 2-[Methyl(phenylmethyl)amino]ethyl 3-Oxo-butanoic Acid
• Synonyme: 2-[benzyl(methyl)amino]ethyl 3-oxobutanoate, 2-(N-methyl-N-benzylamino)ethyl acetoacetate, 2-[(2-Phenylethyl)Amino]Ethyl 3-Oxobutanoate, 2-[Methyl(phenylmethyl)amino]ethyl 3-oxobutanoate, Butanoic acid, 3-oxo-, 2-[methyl(phenylmethyl)amino]ethyl ester

Beschreibung

Applications 2-[Methyl(phenylmethyl)amino]ethyl 3-Oxo-butanoic Acid is used in the synthesis of Nicardipine O-Desmethyl-O-methyl(phenylmethyl)aminoethyl Ester Hydrochloride (N394510), which is a Nicardipine (N394500) impurity. Nicardipine is a dihydropyridine calcium channel blocker. Antianginal; Antihypertensive.
References Satoh, K., et al.: Clin. Exp. Pharmacol. Physiol., 7, 249 (1980), Sorkin, E.M., et al.: Drugs, 33, 296 (1987),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 249.306
• Formel: C₁₄H₁₉NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C14H19NO3/c1-12(16)10-14(17)18-9-8-15(2)11-13-6-4-3-5-7-13/h3-7H,8-11H2,1-2H3
• InChI Key: InChIKey=HPHPTGDPZSEYMB-UHFFFAOYSA-N
• SMILES: CC(=O)CC(=O)OCCN(C)Cc1ccccc1