N-Methyl Pemetrexed

CAS: 869791-42-4

Ref. TR-M325465

Produktinformation

• Name: N-Methyl Pemetrexed
• Synonyme: L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, N-Methylpemetrexed, (2S)-2-[[4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid, Pemetrexed Disodium Heptahydrate Imp. A (EP)
• Marke: TRC
• Beschreibung: Impurity Pemetrexed EP Impurity AApplications N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.References Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005)

Chemische Eigenschaften

• Molekulargewicht: 441.44
• Formel: C₂₁H₂₃N₅O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C21H23N5O6/c1-26-17-16(19(30)25-21(26)22)13(10-23-17)7-4-11-2-5-12(6-3-11)18(29)24-14(20(31)32)8-9-15(27)28/h2-3,5-6,10,14,23H,4,7-9H2,1H3,(H,24,29)(H,27,28)(H,31,32)(H2,22,25,30)/t14-/m0/s1
• InChI Key: InChIKey=JKULRGFPYBAJTE-AWEZNQCLSA-N
• SMILES: Cn1c(N)nc(=O)c2c(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c[nH]c21