4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid

CAS: 114176-52-2

Ref. TR-M326815

Produktinformation

• Name: 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid
• Synonyme: 4-Methyl-3-[[(2RS)-2-(propylamino)propanoyl]amino]thiophene-2-carboxylic Acid, Articaine Hydrochloride Imp. B (EP), Articaine Acid, Articainic acid, 2-Thiophenecarboxylic acid, 4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, 4-methyl-3-[(N-propylalanyl)amino]thiophene-2-carboxylic acid
• CAS: 114176-52-2

Beschreibung

Applications 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid is an impurity of Articaine (A777900), an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand , food surgery and in dentistry.
References Grossman, M., et al.: J. Clin. Pharmacol., 44, 1282 (2004); Oertel, R., et al.: Pharmazie., 53, 646 (1998); Vree, T.B., et al.: Brit. J. Clin. Pharmacol., 44, 29 (1997);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 270.348
• Formel: C₁₂H₁₈N₂O₃S
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C12H18N2O3S/c1-4-5-13-8(3)11(15)14-9-7(2)6-18-10(9)12(16)17/h6,8,13H,4-5H2,1-3H3,(H,14,15)(H,16,17)
• InChI Key: InChIKey=LUPKINKNYDFRIB-UHFFFAOYSA-N
• SMILES: CCCNC(C)C(=O)Nc1c(C)csc1C(=O)O