4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide

CAS: 1061214-09-2

Ref. TR-M327010

Produktinformation

• Name: 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide
• Synonyme: Benzenesulfonamide, 4-[[3-(4-methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]-

Beschreibung

Applications 4-[[3-(4-Methylphenyl)-3-oxo-1-(trifluoromethyl)propylidene]amino]benzenesulfonamide, is an impurity of Celecoxib (C251000), which is a selective cyclooxygenase-2 (COX-2) inhibitor, an anti-inflammatory agent. It is also used in treatment of familial adenomatous polyposis.
References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 384.37
• Formel: C₁₇H₁₅F₃N₂O₃S
• Farbe/Form: Yellow
• InChl: InChI=1S/C17H15F3N2O3S/c1-11-2-4-12(5-3-11)15(23)10-16(17(18,19)20)22-13-6-8-14(9-7-13)26(21,24)25/h2-9H,10H2,1H3,(H2,21,24,25)
• InChI Key: InChIKey=UZXBSHCYSOVOFX-JWGURIENSA-N
• SMILES: Cc1ccc(C(=O)C/C(=N/c2ccc(S(N)(=O)=O)cc2)C(F)(F)F)cc1