2-Methylthio-N6-threonylcarbamoyladenosine

CAS: 70333-82-3

Ref. TR-M330590

Produktinformation

• Name: 2-Methylthio-N6-threonylcarbamoyladenosine
• Synonyme: N-[[[2-(Methylthio)-9-β-D-ribofuranosyl-9H-purin-6-yl]amino]carbonyl]-L-threonine
• Marke: TRC

Beschreibung

Applications 2-Methylthio-N6-threonylcarbamoyladenosine is a hypermodified form of Adenosine (A280400) found in bacterial and eukaryotic tRNAs at the A37 position adjacent to the 3’-end of the anticodon, which is essential for efficient and highly accurate protein translation by the ribosome.
References Arragain, S., et al.: J. Biol. Chem., 285, 28425 (2010)

Chemische Eigenschaften

• Molekulargewicht: 458.446
• Formel: C₁₆H₂₂N₆O₈S
• Farbe/Form: Neat
• InChl: InChI=1S/C16H22N6O8S/c1-5(24)7(14(27)28)18-15(29)19-11-8-12(21-16(20-11)31-2)22(4-17-8)13-10(26)9(25)6(3-23)30-13/h4-7,9-10,13,23-26H,3H2,1-2H3,(H,27,28)(H2,18,19,20,21,29)/t5-,6-,7+,9?,10?,13-/m1/s1
• InChI Key: InChIKey=MMNYGKPAZBIRKN-PLUUKJRDSA-N
• SMILES: CSc1nc(NC(=O)N[C@H](C(=O)O)[C@@H](C)O)c2ncn([C@@H]3O[C@H](CO)C(O)C3O)c2n1