4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside 6-Sulphate Sodium Salt

CAS: 142439-99-4

Ref. TR-M337660

Produktinformation

• Name: 4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside 6-Sulphate Sodium Salt
• Synonyme: 7-[[2-(Acetylamino)-2-deoxy-6-O-sulfo-ß-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one Monosodium Salt, sodium [(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methyl sulfate

Beschreibung

Applications 4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside 6-sulphate sodium salt is a fluorescent substrate for isoenzyme A of N-acetyl-β-D-glucosaminidase (Hexosaminidase A). It can also be used in biological study of characterization of the mutant β-subunit of β-hexosaminidase for dimer formation responsible for the adult form of Sandhoff disease with the motor neuron disease phenotype.
References Yamada, K., et al.: J Biochem, 153, 111 (2013)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 482.41
• Formel: C₁₈H₂₁NO₁₁S·Na
• Farbe/Form: Neat
• InChl: InChI=1S/C18H21NO11S.Na/c1-8-5-14(21)29-12-6-10(3-4-11(8)12)28-18-15(19-9(2)20)17(23)16(22)13(30-18)7-27-31(24,25)26;/h3-6,13,15-18,22-23H,7H2,1-2H3,(H,19,20)(H,24,25,26);/t13-,15-,16-,17-,18-;/m1./s1
• InChI Key: InChIKey=RVIGBTUDFAGRTQ-UHFFFAOYSA-N
• SMILES: CCC(=O)NC1CCc2cccc(OC)c2C1