Methyl 4-Methyl-3-nitrobenzoate-D6

CAS: 7356-11-8

Ref. TR-M339056

Produktinformation

• Name: Methyl 4-Methyl-3-nitrobenzoate-D6
• Synonyme: methyl 2,3,6-trideuterio-5-nitro-4-(trideuteriomethyl)benzoate, 4-Methyl-3-Nitrobenzoic Acid Methyl Ester, Benzoic acid, 4-methyl-3-nitro-, methyl ester, Methyl 3-Nitro-4-Methyl benzoate, Methyl 3-nitro-4-methylbenzoate, Methyl3-Nitro-4-Methylbenzoate, NSC 29086, p-Toluic acid, 3-nitro-, methyl ester
• CAS: 7356-11-8

Beschreibung

Applications Methyl 4-Methyl-3-nitrobenzoate-D6 is an intermediate in the synthesis of Nilotinib-d6 (N465303), which is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia.
References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 201.209
• Formel: C₉H₃D₆NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C9H9NO4/c1-6-3-4-7(9(11)14-2)5-8(6)10(12)13/h3-5H,1-2H3/i1D3,3D,4D,5D
• SMILES: [2H]c1c([2H])c(C([2H])([2H])[2H])c([N+](=O)[O-])c([2H])c1C(=O)OC