Mocetinostat

CAS: 726169-73-9

Ref. TR-M481090

Produktinformation

• Name: Mocetinostat
• Synonyme: N-(2-aminophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamide, Mg 0103, Mgcd 0103, N-(2-Aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]benzamide, N-(2-aminophenyl)-4-((4-pyridin-3-ylpyrimidin-2-ylamino)methyl)benzamide, N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide, benzamide, N-(2-aminophenyl)-4-[[[4-(3-pyridinyl)-2-pyrimidinyl]amino]methyl]-

Beschreibung

Applications Mocetinostat is a multi-targeted histone deacetylase inhibitor used in cancer therapy. Mocetinostat is undergoing clinical trials for the treatment of various cancers including follicular lymphoma, Hodgkin’s lymphoma and acute myelogenous leukemia.
References Ai, T., et al.: Curr. Med. Chem., 19, 475 (2012); Cacasin, M.A., et al.: Circulation Rsch., 110, 739 (2012); Younes, A., et al.: Lancet Oncol., 12, 1222 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 396.44
• Formel: C₂₃H₂₀N₆O
• Farbe/Form: Neat
• InChl: InChI=1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29)
• InChI Key: InChIKey=HRNLUBSXIHFDHP-UHFFFAOYSA-N
• SMILES: Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cccnc3)n2)cc1