(Z)-4-(5-(4-(N'-Methoxycarbamimidoyl)phenyl)furan-2-yl) Benzamide

Ref. TR-M863830

Produktinformation

• Name: (Z)-4-(5-(4-(N'-Methoxycarbamimidoyl)phenyl)furan-2-yl) Benzamide

Beschreibung

Applications (Z)-4-(5-(4-(N'-Methoxycarbamimidoyl)phenyl)furan-2-yl) Benzamide is a by-product in the synthesis of Pafuramidine (P133875). Pafuramidine is a prodrug of Furamidine (F863600, 2HCl); a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.
References Lansiaux, A. et al.: Cancer Res., 62, 7219 (2002); Steck E.A. et al.: Exp. Parasitol., 52, 404 (1981); Balzarini, J. et al.: Incest. New Drugs, 1, 103 (1983); Thuita, J.K., et al.: Acta Trop., 108, 6 (2008); Lanteri, C.A., et al.: Mol. Pharmacol., 70, 1585 (2006)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 335.357
• Formel: C₁₉H₁₇N₃O₃
• Farbe/Form: Green solid
• InChl: InChI=1S/C19H17N3O3/c1-24-22-18(20)14-6-2-12(3-7-14)16-10-11-17(25-16)13-4-8-15(9-5-13)19(21)23/h2-11H,1H3,(H2,20,22)(H2,21,23)
• InChI Key: InChIKey=GESPFFBHIHKFTB-UHFFFAOYSA-N
• SMILES: CO/N=C(\N)c1ccc(-c2ccc(-c3ccc(C(N)=O)cc3)o2)cc1