Methyl 2-Benzyl-5-hydroxy-2H-pyrazole-3-carboxylate

CAS: 52867-49-9

Ref. TR-M948535

Produktinformation

• Name: Methyl 2-Benzyl-5-hydroxy-2H-pyrazole-3-carboxylate
• Synonyme: 1-Benzyl-3-hydroxy-5-methoxycarbonyl-1H-pyrazole,Methyl 2-benzyl-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylate
• CAS: 52867-49-9

Beschreibung

Applications Methyl 2-benzyl-5-hydroxy-2H-pyrazole-3-carboxylate is an intermediate for the synthesis of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro.
References Kotzki, S. et al.: J. Pharm. Exp. Ther., 346, 424 (2013); Selwood, D>et al.: J. Med. CHem., 44, 78 (2001)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 232.24
• Formel: C₁₂H₁₂N₂O₃
• Farbe/Form: White Solid
• InChl: InChI=1S/C12H12N2O3/c1-17-12(16)10-7-11(15)13-14(10)8-9-5-3-2-4-6-9/h2-7H,8H2,1H3,(H,13,15)
• InChI Key: InChIKey=UFYYVUADSYAISN-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc(=O)[nH]n1Cc1ccccc1