Nitroso Valsartan Methyl Ester

CAS: 137862-53-4

Ref. TR-N002960

Produktinformation

• Name: Nitroso Valsartan Methyl Ester
• Synonyme: methyl (2S)-3-methyl-2-[nitroso-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine, CGP 48933, 3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid, L-Valine, N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, Valsartan, Valsartan(Diovan), D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine, L-Valine, N-(1-oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine, n-(1-oxopentyl)-n-((2'-(1h-tetrazol-5-yl)(1,1'-biphenyl)-3-yl)methyl)-l-valine

Beschreibung

Applications Nitroso Valsartan Methyl Ester is an impurity of Valsartan (V095750) a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 394.427
• Formel: C₂₀H₂₂N₆O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C20H22N6O3/c1-13(2)18(20(27)29-3)26(25-28)12-14-8-10-15(11-9-14)16-6-4-5-7-17(16)19-21-23-24-22-19/h4-11,13,18H,12H2,1-3H3,(H,21,22,23,24)/t18-/m0/s1
• InChI Key: InChIKey=JBFJLETZIOUPNG-SFHVURJKSA-N
• SMILES: COC(=O)[C@H](C(C)C)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)N=O