(E)-Naftifine

CAS: 65472-88-0

Ref. TR-N213310

Produktinformation

• Name: (E)-Naftifine
• Synonyme: 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-, 1-Naphthalenemethanamine, N-methyl-N-(3-phenyl-2-propenyl)-, (E)-, 1-Naphthalenemethanamine, N-methyl-N-[(2E)-3-phenyl-2-propenyl]- (9CI), N-Methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, Nafetifine, Naftifine, Naftifungin
• Marke: TRC

Beschreibung

Applications (E)-Naftifine is an intermediate in synthesizing Naftifine N-Oxide (N213110), which is an impurity or metabolite of Naftifine Hydrochloride (N213100), an allylamine antifungal agent.
References Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004)

Chemische Eigenschaften

• Molekulargewicht: 287.4
• Formel: C₂₁H₂₁N
• Farbe/Form: Neat
• InChl: InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3/b11-8+
• InChI Key: InChIKey=QHQKEFQTKKSZEH-IQCSLJNESA-N
• SMILES: COC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@H](C(C)(C)C)NC(=O)O[C@@H]1C[C@H]1CCCCCc1nc3ccc(OC)cc3nc1O2