2,3-Naphthalic Anhydride

CAS: 716-39-2

Ref. TR-N363000

Produktinformation

• Name: 2,3-Naphthalic Anhydride
• Synonyme: benzo[f][2]benzofuran-1,3-dione, 1,3-ββ-Isonaphthofurandione, 2,3-Naphthalenedicarboxylic acid anhydride, 2,3-Naphthalenedicarboxylic anhydride, 2,3-Naphthalic anhydride, Naphtho[2,3-C]Furan-1,3-Dione

Beschreibung

Stability Moisture Sensitive
Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.
References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 198.17
• Formel: C₁₂H₆O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C12H6O3/c13-11-9-5-7-3-1-2-4-8(7)6-10(9)12(14)15-11/h1-6H
• InChI Key: InChIKey=IZJDCINIYIMFGX-UHFFFAOYSA-N
• SMILES: O=C1OC(=O)c2cc3ccccc3cc21