Nifluridide

CAS: 61444-62-0

Ref. TR-N431580

Produktinformation

• Name: Nifluridide
• Synonyme: N-[2-Amino-3-nitro-5-(trifluoromethyl)phenyl]-2,2,3,3-tetrafluoropropanamide, Compound 109168, EL 468, EL 968, L 27, L 27 (pesticide), N1-(2,2,3,3-Tetrafluoropionyl)-3-nitro-5-trifluoromethyl-o-phenylenediamine, N1-(2,2,3,3-Tetrafluoropropionyl)-3'-nitro-5'-trifluoromethyl-o-phenylenediamine, 6'-Amino-a,a,a,2,2,3,3-heptafluoro-5'-nitropropion-m-toluidide, N-[2-Amino-3-nitro-5-(trifluormethyl)phenyl]-2,2,3,3-tetrafluorpropanamid, propanamide, N-[2-amino-3-nitro-5-(trifluoromethyl)phenyl]-2,2,3,3-tetrafluoro-

Beschreibung

Applications Nifluridide also known as L-27 reduces the growth and metastasis of MCF-7 tumor cells in xenografts models and thus may provide a new therapeutic approach for the treatment of breast and other types of cancer. A potential KGFR tyrosine kinase inhibitor. Nifluridide is also used in several pesticidal and insecticide compositions.
References Kesinger, J. W., et al.: Anticancer Res., 35, 47 (2015); Borth, P. W., et al.: J. Econ. Entomol., 79, 1632 (1986)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 349.16
• Formel: C₁₀H₆F₇N₃O₃
• Farbe/Form: Off-White
• InChl: InChI=1S/C10H6F7N3O3/c11-7(12)9(13,14)8(21)19-4-1-3(10(15,16)17)2-5(6(4)18)20(22)23/h1-2,7H,18H2,(H,19,21)
• SMILES: Nc1c(NC(=O)C(F)(F)C(F)F)cc(C(F)(F)F)cc1[N+](=O)[O-]