Nitisinone-13C6

CAS: 1246815-63-3

Ref. TR-N490137

Produktinformation

• Name: Nitisinone-13C6
• Synonyme: 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione-13C6, NTBC-13C6, Nitisone-13C6, Orfadin-13C6, SC 0735-13C6

Beschreibung

Applications Labelled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I.
References Lindstedt, S., et al.: Lancet, 340, 813 (1992), Ellis, M.K., et al.: Toxicol. Appl. Pharmacol., 133, 12 (1995), Lock, E.A., et al.: J. Inherited Metab. Dis., 21, 498 (1998),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 335.18
• Formel: C₈C₆H₁₀F₃NO₅
• Farbe/Form: Light Beige To Brown
• SMILES: O=C(c1ccc(C(F)(F)F)cc1[N+](=O)[O-])[13CH]1[13C](=O)[13CH2][13CH2][13CH2][13C]1=O