NSC 23766 Trihydrochloride

CAS: 1177865-17-6

Ref. TR-N900280

Produktinformation

• Name: NSC 23766 Trihydrochloride
• Synonyme: N6-(2-((5-(Diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine Trihydrochloride

Beschreibung

Applications NSC 23766 is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
References Gao, Y., et. al.: Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al.: Methods Enzymol, 406, 554 (2006)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 530.96
• Formel: C₂₄H₃₈Cl₃N₇
• Farbe/Form: Neat
• InChl: InChI=1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,27,28,29,30)
• InChI Key: InChIKey=DEFBCZWQLILOJF-UHFFFAOYSA-N
• SMILES: CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1