NVP-BKM 120

CAS: 944396-07-0

Ref. TR-N925760

Produktinformation

• Name: NVP-BKM 120
• Synonyme: BKM 120, 5-(2,6-di-4-Morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine, 2-Pyridinamine, 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-, 5-(2,6-Dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine, Bkm 120, Bkm 120Nx, Bkm120, Buparlisib, Nvp-Bkm 120, Nvp-Bkm120
• CAS: 944396-07-0

Beschreibung

Stability Hygroscopic
Applications NVP-BKM 120 is a novel anti-tumor active compound that is selective in that it inhibits specifically PI3 kinase activating cell death in glioma cells. Glioma cells being those that proliferate from tumors in the brain or the spine.
References Koul, D. et al.: Clin. Cancer Res., 18, 184 (2012);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 410.39
• Formel: C₁₈H₂₁F₃N₆O₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
• InChI Key: InChIKey=CWHUFRVAEUJCEF-UHFFFAOYSA-N
• SMILES: Nc1cc(C(F)(F)F)c(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)cn1