(R)-Omeprazole

CAS: 119141-89-8

Ref. TR-O634995

Produktinformation

• Name: (R)-Omeprazole
• Synonyme: 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, 5-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulphinyl]-1H-benzimidazole, 1H-Benzimidazole-1-acetic acid, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (+)-, 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, (+)-Omeprazole, (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole, (R)-Esomeprazole, 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (R)-, 1H-Benzimidazole, 5-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (R)-, 1H-Benzimidazole, 6-methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, 1H-Benzimidazole-1-acetic acid, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, (+)-, 2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine, 5-Methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole, Losec, Mepral, Mopral, Omepral, Omerprazole, R-(+)-Omeprazole, Zoltum

Beschreibung

Stability Hygroscopic
Applications (R)-Omeprazole is the R-enantiomer of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.
References Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999); Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003); Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 345.42
• Formel: C₁₇H₁₉N₃O₃S
• Farbe/Form: Light Brown to Black Solid
• InChl: InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)/t24-/m1/s1
• InChI Key: InChIKey=SUBDBMMJDZJVOS-XMMPIXPASA-N
• SMILES: COc1ccc2[nH]c([S@](=O)Cc3ncc(C)c(OC)c3C)nc2c1