OSI-420-D4, Free Base (Desmethyl Erlotinib-D4)

CAS: 1216420-11-9

Ref. TR-O702252

Produktinformation

• Name: OSI-420-D4, Free Base (Desmethyl Erlotinib-D4)
• Synonyme: 2-[7-(2-Methoxyethoxy)-4-[(2,3,4,6-tetradeuterio-5-ethynylphenyl)amino]quinazolin-6-yl]oxyethanol, 2-[[4-[(3-Ethynylphenyl-2,4,5,6-d4)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol, CP 473420-d4, Desmethyl erlotinib-d4, OSI-420-d4 (free base), 6-O-Desmethylerlotinib-D4 (phenyl-2,4,5,6-D4), N-(3-Ethynylphenyl-2,4,5,6-d4)-6-(2-hydroxyethoxy)-7-(2-methoxyethoxy)-4-quinazolinamine
• CAS: 1216420-11-9

Beschreibung

Applications A labelled metabolite of Erlotinib (E625000), an anti cancer agent.
References Rusch, V., et al.: Cancer Res., 53, 2379 (1993), Fontanini, G., et al.: Clin. Cancer Res., 4, 241 (1998), Comis, R., et al.: Oncologist, 10, 467 (2005), Ling, J., et al.: Drug Metab. Dispos., 34, 420 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 383.43
• Formel: C₂₁H₁₇D₄N₃O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C21H21N3O4/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21/h1,4-6,11-14,25H,7-10H2,2H3,(H,22,23,24)/i4D,5D,6D,11D
• SMILES: [2H]c1c([2H])c(C#C)c([2H])c(Nc2ncnc3cc(OCCOC)c(OCCO)cc23)c1[2H]