Ouabain Octahydrate

CAS: 11018-89-6

Ref. TR-O714500

Produktinformation

• Name: Ouabain Octahydrate
• Synonyme: Ouabain, 3β-[(6-deoxy-α-l-mannopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxy- 5β,14β-card-20(22)-enolide
• Marke: TRC

Beschreibung

Applications A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);

Chemische Eigenschaften

• Molekulargewicht: 728.77
• Formel: C₂₉H₄₄O₁₂·8H₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-;;;;;;;;/m0......../s1
• InChI Key: InChIKey=LPMXVESGRSUGHW-UHFFFAOYSA-N
• SMILES: CC1OC(OC2CC(O)C3(CO)C4C(O)CC5(C)C(C6=CC(=O)OC6)CCC5(O)C4CCC3(O)C2)C(O)C(O)C1O