(S)-Oxiran-2-ylmethyl (2-(Trimethylammonio)ethyl) Phosphate

Ref. TR-O715900

Produktinformation

• Name: (S)-Oxiran-2-ylmethyl (2-(Trimethylammonio)ethyl) Phosphate
• Synonyme: 2-[dimethyl(methyl)azaniumyl]ethyl [(2S)-oxiran-2-yl]methyl phosphate

Beschreibung

Applications (S)-Oxiran-2-ylmethyl (2-(Trimethylammonio)ethyl) Phosphate is an intermediate for the synthesis of (S)-α-Glycerophosphocholine (G601585), which is a parasympathomimetic acetylcholine precursor which may have potential for the treatment of Alzheimer's disease and other dementias.
References Moreno, M., et al.: Clin. Ther., 25, 178 (2003); Parnetti, L., et al.: J. Neurol. Sci., 257, 264 (2007); Doggrell, S., et al.: Expert Opin. Investig. Drugs, 12, 1633 (2003)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 238.198
• Formel: C₈H₁₇NO₅P
• Farbe/Form: Neat
• InChl: InChI=1S/C8H18NO5P/c1-9(2,3)4-5-13-15(10,11)14-7-8-6-12-8/h8H,1,4-7H2,2-3H3,(H,10,11)/q+2/p-1/t8-/m0/s1
• SMILES: [CH2+][N+](C)(C)CCOP(=O)([O-])OC[C@@H]1CO1