(S,S)-Oxaliplatin

CAS: 61758-77-8

Ref. TR-O845080

Produktinformation

• Name: (S,S)-Oxaliplatin
• Synonyme: Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]-, (SP-4-2)-, Platinum, (1,2-cyclohexanediamine-kappaN,kappaN')[ethanedioato(2-)-kappaO1,kappaO2]-, [SP-4-2-[1S-(trans)]]-, Platinum, [(1S,2S)-1,2-cyclohexanediamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]- (9CI), 1,2-Cyclohexanediamine, platinum complex, (1S-trans)-, [(1S,2S)-1,2-Cyclohexanediamine-kappaN1,kappaN2][ethanedioato(2-)-kappaO1,kappaO2]platinum, NSC 266042, Platinum, (1,2-cyclohexanediamine-N,N')[ethanedioato(2-)-O,O']-, [SP-4-2-(1S-trans)]-, (SP-4-2)-[(1S,2S)-Cyclohexane-1,2-diamine-kappaN,kappaN'][ethanedioato(2-)-kappaO1,kappaO2]platinum, Oxaliplatin Imp. D (EP), Oxaliplatin Related Compound D (USP)

Beschreibung

Applications The (S,S) Oxaliplatin isomer. Third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic.
References Kidani, Y., et al.: J. Med. Chem., 21, 1315 (1978), Kizu, R., et al.: Cancer Chemother. Pharmacol., 31, 475 (1993), Levi, F., et al.: Eur. J. Cancer, 29A, 1280 (1993), Simpson, D., et al.: Drugs, 63, 2127 (2003),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 397.29
• Formel: C₈H₁₄N₂O₄Pt
• Farbe/Form: White
• InChl: (H,3,4)(H,5,6), InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8, 3-1(4)2(5)6, , /m0../s1, /q, , /h5-6H,1-4,7-8H2, +2/p-2/t5-,6-
• InChI Key: InChIKey=ZROHGHOFXNOHSO-USPAICOZSA-L