7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid

CAS: 52029-86-4

Ref. TR-O847425

Produktinformation

• Name: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid
• Synonyme: 11-oxo-3,10-diazapentacyclo[10.7.1.0^{2,10}.0^{4,9}.0^{16,20}]icosa-1(19),2,4(9),5,7,12(20),13,15,17-nonaene-17-carboxylic acid, Sto-609
• CAS: 52029-86-4

Beschreibung

Applications 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic Acid is a calcium/calmodulin-dependent protein kinase inhibitor and was found to upregulate various AhR target genes in human macrophages.
References Monteiro, P., et al.: Drug. Meta. Dispos., 36, 2556 (2008); Tokumitsu, H., et al.: J. Biol. Chem., 278, 10908 (2003); Tokumitsu, H., et al.: J. Biol. Chem., 277, 15813 (2002);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 374.346
• Formel: C₁₉H₁₀N₂O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C19H10N2O3/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18/h1-9H,(H,23,24)
• InChI Key: InChIKey=MYKOWOGZBMOVBJ-UHFFFAOYSA-N
• SMILES: O=C(O)c1ccc2c3c1cccc3c(=O)n1c3ccccc3nc21