2-Oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid tert-Butyl Ester

CAS: 161468-45-7

Ref. TR-O855310

Produktinformation

• Name: 2-Oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid tert-Butyl Ester
• Synonyme: tert-Butyl 2-Oxo-2,3-dihydro-1H-benzimidazole-1-carboxylate, 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic Acid 1,1-Dimethylethyl Ester, N-Boc-2-Hydroxybenzimidazole

Beschreibung

Applications 2-Oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid tert-Butyl Ester is an substituent in the synthesis of Domperidone (D531100), a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier and is used as an anti-emetic agent.
References Badarau, E., et al.: J. Enzyme. Inhib. Med. Chem., 25, 301 (2010); Guichard, G., et al.: J. Org. Chem., 64. 8702 (1999);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 234.25
• Formel: C₁₂H₁₄N₂O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C12H14N2O3/c1-12(2,3)17-11(16)14-9-7-5-4-6-8(9)13-10(14)15/h4-7H,1-3H3,(H,13,15)
• InChI Key: InChIKey=GMUWCTKADZFKLT-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)n1c(=O)[nH]c2ccccc21