N-Oxo Prucalopride

CAS: 1900715-98-1

Ref. TR-O870073

Produktinformation

• Name: N-Oxo Prucalopride
• Synonyme: 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-1-oxido-4-piperidinyl]-7-benzofurancarboxamide

Beschreibung

Applications N-Oxo Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 383.87
• Formel: C₁₈H₂₆ClN₃O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C18H26ClN3O4/c1-25-9-2-6-22(24)7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-26-17(13)14/h11-12H,2-10,20H2,1H3,(H,21,23)
• InChI Key: InChIKey=CRUBJJQTENRFEL-WJDAMSDJSA-N
• SMILES: [2H]C([2H])(CO)C([2H])(O)C([2H])([2H])CCCC(=O)OC