13-Oxyingenol Dodecanoate

CAS: 54706-70-6

Ref. TR-O870770

Produktinformation

• Name: 13-Oxyingenol Dodecanoate
• Synonyme: Dodecanoic Acid Ingenol Ester, [1aR-(1aa,2ß,5ß,5aß,6ß,8aa,9a,10aa)]-1,1a,2,5,5a,6,9,10-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-10aH-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-10a-yl Ester Dodecanoic Acid, 10aH-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecene Dodecanoic Acid Deriv.

Beschreibung

Applications 13-Oxyingenol Dodecanoate is a diterpene compound with antinematodal activity. Derivative of Ingenol (I655795), the analogue of Ingenol 3-Angelate (I655800), which has anti-tumor activity when used topically for the treatment of actinic keratosis.
References Shi, J. et al.: Z. Naturforsch. C: J. Biosci., 63, 59 (2008); Ogbourne, S.M., et al.: Cancer. Res., 64, 2833 (2004); Zayed, S.M., et al.: J. Cancer. Res. Clin. Oncol., 127, 40 (2001);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 546.74
• Formel: C₃₂H₅₀O₇
• Farbe/Form: Neat
• InChl: InChI=1S/C32H50O7/c1-6-7-8-9-10-11-12-13-14-15-24(34)39-31-18-21(3)30-17-20(2)26(35)32(30,38)27(36)22(19-33)16-23(28(30)37)25(31)29(31,4)5/h16-17,21,23,25-27,33,35-36,38H,6-15,18-19H2,1-5H3/t21-,23?,25-,26+,27-,30+,31?,32-/m1/s1
• InChI Key: InChIKey=FEZDDYPHEHMXLF-RFSICKADSA-N
• SMILES: CCCCCCCCCCCC(=O)OC12C[C@@H](C)[C@]34C=C(C)[C@H](O)[C@@]3(O)[C@H](O)C(CO)=C[C@H](C4=O)[C@@H]1C2(C)C