Phenyl (4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamate Hydrochloride

CAS: 2514745-52-7

Ref. TR-P106910

Produktinformation

• Name: Phenyl (4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamate Hydrochloride
• Marke: TRC
• Beschreibung: Applications Phenyl (4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamate Hydrochloride is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010)

Chemische Eigenschaften

• Molekulargewicht: 443.89
• Formel: C₂₁H₂₄F₃N₃O₂·HCl
• Farbe/Form: Neat
• InChl: InChI=1S/C21H24F3N3O2.ClH/c1-2-26-10-12-27(13-11-26)15-16-8-9-17(14-19(16)21(22,23)24)25-20(28)29-18-6-4-3-5-7-18;/h3-9,14H,2,10-13,15H2,1H3,(H,25,28);1H
• InChI Key: InChIKey=LYNXGRRTGPSORV-UHFFFAOYSA-N
• SMILES: CCN1CCN(Cc2ccc(NC(=O)Oc3ccccc3)cc2C(F)(F)F)CC1.Cl