Palbociclib-d4

CAS: 571190-30-2

Ref. TR-P139901

Produktinformation

• Name: Palbociclib-d4
• Synonyme: 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one-d4, 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one-d4, Ibrance-d4, PD 0332991-d4, PD 332991-d4, PD 991-d4
• Marke: TRC
• Beschreibung: Applications Palbociclib-d4 is an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)

Chemische Eigenschaften

• Molekulargewicht: 451.56
• Formel: C₂₄H₂₅D₄N₇O₂
• Farbe/Form: Light Yellow
• InChl: InChI=1S/C29H37N7O4/c1-18-22-17-31-27(33-25(22)36(20-8-6-7-9-20)26(38)24(18)19(2)37)32-23-11-10-21(16-30-23)34-12-14-35(15-13-34)28(39)40-29(3,4)5/h10-11,16-17,20H,6-9,12-15H2,1-5H3,(H,30,31,32,33)
• InChI Key: InChIKey=AHJRHEGDXFFMBM-YQUBHJMPSA-N
• SMILES: [2H]C1([2H])CN(c2ccc(Nc3ncc4c(C)c(C(C)=O)c(=O)n(C5CCCC5)c4n3)nc2)CC([2H])([2H])N1