(S,S)-Palonosetron-d3 Hydrochloride

CAS: 1246816-81-8

Ref. TR-P165802

Produktinformation

• Name: (S,S)-Palonosetron-d3 Hydrochloride
• Synonyme: (3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one-d3 Hydrochloride, Aloxi-d3, Onicit-d3, RS-25259-197-d3

Beschreibung

Applications Serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 335.89
• Formel: C₁₉H₂₂D₃ClN₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1/i11D2,17D
• InChI Key: InChIKey=OLDRWYVIKMSFFB-RAVRUBKISA-N
• SMILES: Cl.[2H]C1([2H])[C@H]2CCCc3cccc(c32)C(=O)N1[C@]1([2H])C[N@]2CC[C@@H]1CC2