Para-Naphthol Duloxetine

CAS: 949095-98-1

Ref. TR-P191860

Produktinformation

• Name: Para-Naphthol Duloxetine
• Synonyme: 4-Bromobenzhydrol, Duloxetine Hydrochloride Imp. C (EP), Duloxetine Imp. C (EP), 1-Naphthalenol, 4-[3-(methylamino)-1-(2-thienyl)propyl]-, 4-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol, 4-[(1RS)-3-(Methylamino)-1-(thiophen-2-yl)propyl]naphthalen-1-ol, Duloxetine Hydrochloride Impurity C, Duloxetine Impurity C
• CAS: 949095-98-1

Beschreibung

Impurity Duloxetine EP Impurity F
Applications Para-Naphthol Duloxetine is an impurity of Duloxetine (D721000), an antidepressant and a dual serotonin and norepinephrine reuptake inhibitor (SNRI) (1,2). Exhibits linear pharmacokinetics in mice and is not associated in any drastic changes of blood pressure or heart rate (3).
References 1. Wong, D. et al.: Neuropsychopharmacology. 1993 Jan;8(1):23-33.2. Fuller, R. et al.: J Pharmacol Exp Ther. 1994 Apr;269(1):132-6. 3. Sharma, A. et al.: J Clin Pharmacol. 2000 Feb;40(2):161-7.

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 297.42
• Formel: C₁₈H₁₉NOS
• Farbe/Form: Neat
• InChl: InChI=1S/C18H19NOS/c1-19-11-10-16(18-7-4-12-21-18)14-8-9-17(20)15-6-3-2-5-13(14)15/h2-9,12,16,19-20H,10-11H2,1H3
• InChI Key: InChIKey=OJXMJLCWKLPCHB-UHFFFAOYSA-N
• SMILES: CNCCC(c1cccs1)c1ccc(O)c2ccccc12