USP Paroxetine Related Compound E Mixture

CAS: 1012886-75-7, 110429-35-1

Ref. TR-P205790

Produktinformation

• Name: USP Paroxetine Related Compound E Mixture
• Synonyme: 1-Methyl-4-(p-fluorophenyl)-1,2,3,6-tetrahydropyridine in Paroxetine Hydrochloride Matrix, 98% Paroxetine Hydrochloride Spiked with 2% 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride
• Marke: TRC
• Beschreibung: Applications USP Paroxetine Related Compound E Mixture is a reference standard composed of Paroxetine Hydrochloride (P205750) spiked with 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220). Paroxetine Hydrochloride (P205750) is a selective serotonin reuptake inhibitor. Used as an antidepressant. 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine Hydrochloride (F595220) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982); Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),

Chemische Eigenschaften

• Molekulargewicht: 557.07
• Formel: C₁₉H₂₀FNO₃·C₁₂H₁₄FN·HCl
• Farbe/Form: Neat
• InChl: InChI=1S/C19H20FNO3.C12H14FN.ClH/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;1-14-8-6-11(7-9-14)10-2-4-12(13)5-3-10;/h1-6,9,14,17,21H,7-8,10-12H2;2-6H,7-9H2,1H3;1H/t14-,17-;;/m0../s1
• InChI Key: InChIKey=BJTXZKPAZICCJY-YHOFXEKLSA-N
• SMILES: CN1CC=C(c2ccc(F)cc2)CC1.Cl.Fc1ccc([C@@H]2CCNC[C@H]2COc2ccc3c(c2)OCO3)cc1