N2-(2-Chloropyrimidin-4-yl)-N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N4-methylpyrimidine-2,4-diamine

CAS: 1252927-44-8

Ref. TR-P210920

Produktinformation

• Name: N2-(2-Chloropyrimidin-4-yl)-N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N4-methylpyrimidine-2,4-diamine
• Synonyme: 2,4-Pyrimidinediamine, N2-(2-chloro-4-pyrimidinyl)-N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N4-methyl-, N2-(2-Chloro-4-pyrimidinyl)-N2,N4-bis(2,3-dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine
• Marke: TRC
• Beschreibung: Applications This compound is an impurity of Pazopanib (P210925). Pazopanib is an oral angiogenesis inhibitor targeting VEGFR and PDGFR.References Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009),

Chemische Eigenschaften

• Molekulargewicht: 525.007
• Formel: C₂₇H₂₅ClN₁₀
• Farbe/Form: Neat
• InChl: InChI=1S/C27H25ClN10/c1-16-20-8-6-18(14-22(20)33-36(16)4)35(3)24-10-13-30-27(32-24)38(25-11-12-29-26(28)31-25)19-7-9-21-17(2)37(5)34-23(21)15-19/h6-15H,1-5H3
• InChI Key: InChIKey=TXUNTXQWEARYOT-UHFFFAOYSA-N
• SMILES: Cc1c2ccc(N(C)c3ccnc(N(c4ccc5c(C)n(C)nc5c4)c4ccnc(Cl)n4)n3)cc2nn1C